35 Great Dane mixes you need to know more about right now

The Great Dane is a purebred dog and it may seem silly, but you can crossbreed him with other pups.

By doing so, you can create a variety of coat colors and patterns such as brindle, fawn, harlequin, and black.

Great Dane standing in the field
A big Great Dane standing on the grass

Your hybrid pup will have different temperaments as well.

Adding a Great Dane mix to your family is a wonderful idea and is certainly something to look into.

What is a Great Dane?

Originating from Germany, the Great Dane is a friendly, loveable, and loyal pooch. Deemed the gentle giant, this pup is a great choice to add to your family.

Did you know this dog breed can be mixed with a lot of other breeds? This may not give them a longer lifespan, due to their massive size.

In fact, their size causes them to be prone to some health issues, such as hip dysplasia or bloat.

But you can have all sorts of types of Great Danes.

If you’re looking to mix the Great Dane’s well temperament along with its sleek looks with another pup to fit your home, look no further!

35 of the most popular and adorable Great Dane mixes

Have you ever thought about what a Great Dane would look like mixed with other dogs both large and small?

Keep on reading to check out some of the most popular hybrid Great Danes!

1. Chihuahua Great Dane mix (AKA Chi-Dane-Dane)

A Chi-Dane-Dane standing on the grass and wearing a floral scarf
A Chihuahua Great Dane mix standing adorably – Image source

Also called the Great Mexican Dog, this hybrid offspring of the Great Dane and Chihuahua may sound unbelievable, but they exist! Not using the natural breeding process, though.

When the expensive yet risky process is successful, though, the resulting Great Dane Chihuahua mix has a unique look and has Small Dog Syndrome despite being twice the size of the Chi.

This doggo is loyal, friendly, and affectionate, though. They make great watchdogs even if they don’t realize that they’re not as big as Great Danes.

2. Pitbull Great Dane mix (AKA Great Danebull)

A Great Danebull standing and wearing a black body collar
Meet Duke, a Pitbull Great Dane mix on a walk – Image source

This mixed pup will make a wonderful family pet. Despite the Pitbull Terrier’s reputation and the Great Dane’s size, this breed is gentle, great with kids, and will love attention from their owners.

However, they are a fairly active pooch, so they’ll need a decent amount of playtime and exercise each day.

The Great Danebull is a large dog with short, dense coats that are smooth. They’ll typically have a rectangle-shaped head, taking after their Great Dane parent.

Taking after their Pitbull parent, they’ll most likely have half-pricked ears.

3. Labrador Retriever Great Dane mix (AKA Labradane)

A shiny black Labradane sitting near a lake
A Labrador Retriever Great Dane mix on an adventure – Image source

The Labradane is active, social, and highly affectionate with their family. They’re loyal and gentle, making them great with kids as well as the elderly.

This mixed breed gets many great qualities and traits from both parents and will make a great addition to any home.

This is another big dog, whereas the Great Dane is giant and the Labrador is medium to large. So, you’ll need to make sure you have the room for this pooch.

This fido will have a slender body, but don’t let that deceive you – they’re quite strong. They’ll most likely take after their Great Dane parent in having a short and glossy coat.

4. Poodle Great Dane mix (AKA Great Danoodle)

A Danedoodle looking looking directly at a camera and laying on the grass
A curly Poodle Great Dane mix laying with toys

Also known as the Great Danepoos, this Poodle mix breed will make a great family pet. They’re calm, loving, and will enjoy spending time with people and other animals.

This doggo will most likely take after its Poodle parent with a coat that’s either short or medium and wavy or curly. It will also have floppy ears and a muzzle like the Poodle but will have a rectangle head like the Great Dane.

5. Husky Great Dane mix (AKA Great Danesky)

A Great Danesky standing on a tree trunk smiling
Meet Arya, a long and slim Husky Great Dane mix – Image source

The Siberian Husky mix and the Great Dane is a wonderful companion for anyone. This pup is independent, playful, and social. They’ll be friendly with people, other dogs, and kids.

This mixed breed will be a large dog, though, so you’ll want to make sure you have the room for him in your house.

The size of this pooch will vary, like all mixed breeds, but the mother’s size will give you a good indication of how big your Great Danesky may get. Also, the size between males and females will differ.

6. German Shepherd Great Dane mix (AKA Great Shepherd)

A Great Shepherd puppy laying on the floor comfortably
Meet Mia Mae, a German Shepherd Great Dane mix – Image source

This one is another breed that will be large to giant in size. The German Shepherd and Great Dane mix may look like either parent.

So, you may get a Great Shepherd that looks most like one parent breed over the other, or it might look like a perfect mix.

This Shepherd mix will be a great choice to bring home to your family. They’re laid-back, patient, and will make an incredible watchdog.

Plus, they’re easy to train and friendly with others. They’ll enjoy having a lot of attention from their family.

7. Boxer Great Dane mix (AKA Boxane)

A brown Boxane laying on a blanket
Meet Lincoln, a comfortable Boxer Great Dane mix – Image source

With high energy levels, this Boxer and Great Dane mix is curious with usually friendly. They’ll be a stubborn pup, making them harder to train.

They will do okay with other pets or dogs in the house, but they might be stand-offish with strange dogs.

The Boxane will be a large dog with a short coat. They’ll have a sturdy build with large feet and folded ears.

8. Golden Retriever Great Dane mix (AKA Great Golden Dane)

A black Great Golden Dane laying on the grass
Meet Oakley, a Golden Retriever Great Dane mix with a red collar – Image source

This pooch is a big one – they’re large, being over two feet tall. The male Great Golden Danes will be taller than the females, but the females will be longer.

The coat will vary, depending on whether the pup takes after its Golden Retriever parents or its Great Dane parent.

They might have a short, single-layer coat from the Great Dane or a dense undercoat covered by a weather-resistant medium layer from the Golden Retriever. 

The Great Golden Dane will be a fun doggo to have another. They’re friendly and social with others.

This crossbreed is typically good with children and may get protective from their Great Dane parents. They’re easy to train if started early. 

9. Rottweiler Great Dane mix (AKA Weiler Dane)

A resting Weiler Dane on a couch with red plaid harness
Meet Zeus, a Rottweiler Great Dane mix puppy laying down – Image source

The Rottweiler and Great Dane mix are gentle and great with kids, but they can be stubborn.

If you’re not a fitness buff, this may be a pooch for you. The Weiler Dane has low energy, but they’ll enjoy a good daily walk.

This fido will be large with the Great Dane’s height and the muscular build and broad chest of the Rottweiler.

10. Great Pyrenees Great Dane mix (AKA Great Pyredane)

a Great Pyredane tilting head and laying on the grass
Meet Amsley, a Great Pyrenees Great Dane mix puppy looking adorable – Image source

The Great Pyredane will be easygoing and calm most of the time. They’ll tolerate young kids and may have protective tendencies from their Great Dane parents.

However, this mixed breed is relatively independent and sensitive. They have a moderate energy level, so you won’t have to worry about hyperactivity.

This pooch is a giant breed, though. You’ll need to make sure that you have the room in your house to fit this pup.

This Great Pyrenees and Great Dane mix may look like either parent but will most likely have the tail and coat of the Great Dane.

11. American Bulldog Great Dane mix (AKA American Bull Dane)

An American Bull Dane on a dog bed
Meet Henry, an American Bulldog Great Dane mix laying comfortably – Image source

The American Bull Dane is an affectionate pup that’s intelligent and independent. They’ll need to have proper socialization, and training may be difficult with this pooch.

However, the American Bulldog and Great Dane mix have fairly low energy levels. They’ll enjoy lounging on the couch beside you all day long.

This is a giant dog that will most likely take after its Great Dane parent with a smooth, shiny coat, muscular body, and long tapered tail. It could still look like either parent, though.

12. Border Collie Great Dane mix (AKA Great Border Collie)

A Great Border Collie laying on the grass
Meet Falcon, a Border Collie Great Dane mix with a judgment look – Image source

The Border Collie and Great Dane mix will be loyal, intelligent, and friendly. This pup will get along with other pets and dogs. They’re easy to train but will need plenty of room to run around.

Having an active family is where they’ll thrive best.

This medium-to-large-sized pooch can take after either the Great Dane or Border Collie in terms of looks. The genes will vary from pup to pup, even in the same litter.

13. Saint Bernard Great Dane mix (AKA Bernadane)

A Bernadane playing on the snow
Meet Doug, a Saint Bernard Great Dane mix loving the snowy day – Image source

Also called a Great Bernard or Saint Dane, this doggo is a giant that can grow as tall as 32 inches (81 cm) and weigh as much as 200 pounds (90 kg).

This is another mixed breed that can look like either Saint Bernard or Great Dane, but they will typically have a short, straight coat.

The Bernadane will make a great family dog. They’re protective, good with kids (and other dogs and pets), and social. They’ll be easy to train and are active so that they will want plenty of playtime.

14. Irish Wolfhound Great Dane mix (AKA Irish Dane)

An Irish Dane laying down on a wooden floor
Meet Atlas, an Irish Wolfhound Great Dane mix on a mountain – Image source

The Irish Dane is also known as the Wolfhound Dane, and it’s a mixture between an Irish Wolfhound and Great Dane.

This gentle, friendly pooch will love to cuddle with you, despite their size. They may be prone to separation anxiety when you’re away for too long. They’re pretty social and will enjoy having other pets around.

This mixed breed is huge and will have a muscular build. Its thick coat will be short to medium in length. While the genes will vary, it will most likely have the head, eyes, and ears of its Great Dane parent.

15. English Mastiff Great Dane mix (AKA Daniff)

A majestic Daniff standing on the snow
Meet Sirodin, an English Mastiff Great Dane mix standing proudly on the snow – Image source

You’ll need patience and consistency with the Daniff when it comes to training. This fido has high energy levels and will need proper socialization with other people, pets, kids, and strangers. 

They can have protective traits from their English Mastiff parent and a high prey drive trait from their Great Dane parent, so they’ll make a great guard dog.

The Daniff will mostly resemble the Great Dane. It might have a muscular build with a large head and floppy ears. The folds on their face will come from their Mastiff parent.

16. Doberman Pinscher Great Dane mix (AKA Doberdane)

A black Doberdane wearing a black harness
Meet Loki, a Doberman Pinscher Great Dane mix with a perfect posture – Image source

The Doberdane will be an extremely friendly, playful, and loyal companion. They’ll make a wonderful watchdog (but won’t attack or be aggressive), especially for young kids.

However, due to their size and high energy levels, they will play rough. Having young kids might not be a good fit unless they are supervised.

The size of this mutt is no joke. The Doberman Pinscher and Great Dane create a giant dog. This mixed breed will have a long, muscular body with a broad chest. Its coat will typically be smooth and soft with floppy ears.

17. Great Dasenji Basenji Great Dane mix (AKA Great Dasenji)

A Great Dasenji sitting on a bench and smiling
A Great Dasenji Basenji Great Dane mix – Image source

The Great Dasenji is gentle, affectionate, curious, and intelligent. They will need engaging games and activities as well as a lot of attention.

They have a medium energy level and may inherit some stubborn traits from their Basenji parent.

This pooch can look like either parent but will most likely have the muzzle, eyes, and ears from the Basenji parent. It will also most likely have the feet from the Great Dane. This mixed breed will have a short, smooth coat.

18. American Foxy Hound Great Dane mix (AKA American Foxy Dane)

The American Foxhound and Great Dane mix will be medium in size. They’ll look like a perfect mixture of their parents, although the looks of this mixed breed will vary.

This pooch is docile, kind, and affectionate. They’ll get along just fine with children and other pets, but they might be a little shy or timid around strangers.

With their moderate energy levels, they’ll enjoy long walks, games of fetch, and other various activities.

The American Foxy Dane will also make a great watchdog. They will not get aggressive unless they feel like they need to.

19. Weimaraner Great Dane mix (AKA Great Wiemer)

A Great Weimer puppy crossed-leg and wearing a pink and blue collar
Meet Logan, a Weimaraner Great Dane mix puppy being a good boy – Image source

This giant-sized mutt can look like either parent but will most likely have a smooth, short coat.

They can sometimes inherit long hair from the Weimaraner parent, and this will give the pup a double-layered coat with a light undercoat with a dense, wavy overcoat.

While friendly and gentle, this big doggo may get too rambunctious during their playtime.

They’re good with kids but will need supervision to make sure they stay calm and gentle. They will get bored quickly and need plenty of room to play.

The Great Weimar is a loyal companion and is prone to separation anxiety if left alone for too long.

20. Greater Swiss Mountain Dog Great Dane mix (AKA Greater Swiss Mountain Dane)

A Greater Swiss Mountain Dane loving the water
Meet Rosco, a water-loving Greater Swiss Mountain Dog Great Dane mix – Image source

This mutt will have a muscular body with a short and thick coat, but he can take after either the Great Dane parent or the Greater Swiss Mountain Dog. He’ll be a big boy and will still try to be a lap dog despite that.

The Greater Swiss Mountain Dane is gentle and affectionate. He’ll be alert and protective of his family and get along well with younger kids if introduced to them as a puppy.

This pooch can be a stubborn one, making training an experience.

21. Anatolian Shepherd Dog Great Dane mix (AKA Plush Danois)

A patient Plush Danois laying crossed leg on the floor
Meet Lars, an Anatolian Shepherd Dog Great Dane mix posing – Image source

This fido can be aggressive and too protective at times. While they’ll make a good guard dog, they’re territorial and may not accept strangers.

The Anatolian Shepherd and Great Dane mix will need to be taught what’s right and wrong.

Socialization will help with this a lot. A place like a dog park will be an excellent way to introduce them to other dogs and strangers. They also have a high energy level, allowing them to let some of that out.

The Plush Danois is a big dog with a muscular body, a long neck, and a long, curvy tail.

They may look like either parent but will typically have a straight, dense coat that’s medium in length. It can have many different coat colors as well.

22. Catahoula Leopard Dog Great Dane mix (Great Catahoula)

A half body image of a happy Great Catahoula
Meet Lola, a Catahoula Leopard Dog Great Dane mix laying on the floor – Image source

The Great Catahoula will make an excellent watchdog as they might have a high protective instinct from their Catahoula Leopard Dog parent. They may be stubborn as well, making training harder.

This pup will be friendly and affectionate, though, allowing them to be a great best friend.

This fido can look like either parent with moderate shedding. If you want your house to be free of fur, weekly brushing is a must.

23. Beagle Great Dane mix (AKA Great Dangle)

A shiny Great Dangle laying on the grass
Meet Rhea, a Beagle Great Dane mix lounging outdoors – Image source

This Beagle and Great Dane mix can look like either parent but a large dog in size, even though Beagles are a medium size. The females will often be smaller than males.

This pooch has high energy levels and will need plenty of exercises, especially if you don’t want your furry friend to become obese.

They’re playful and social, so running around the dog park will be fun for both you and your companion.

However, the Great Dangle can be stubborn, making training difficult.

24. Bull Mastiff Great Dane mix (AKA Bull Daniffs)

A handsome Bull Daniff laying down smiling
Meet Tank, a lovable Bull Mastiff Great Dane mix – Image source

This Mastiff mix is intelligent, loyal, and confident. They may be wary of strangers but will not be aggressive, making them a wonderful watchdog.

They’ll be good with children and will be easy to train. However, if left alone for too long, they may get separation anxiety.

This mutt is typically heavier than the Great Dane with a muscular build, a large head, and floppy ears. Genetics will be unpredictable, though, and this pup can also look like the Bull Mastiff.

25. Australian Shepherd Great Dane mix (AKA Australian Shepherd Great Dane)

An active Australian Shepherd Great Dane on a walk
Meet Mazie, an Australian Shepherd Great Dane mix walking on the wilderness – Image source

This mixed breed is easy to train and intelligent, causing them to be a bit on the stubborn side.

They’ll need a lot of mental and physical challenges to keep them active and on their toes. This pup is loyal to its family and social with others.

The Australian Shepherd Great Dane will be a large dog and can take after any parent.

26. Dalmatian and Great Dane mix (AKA Great Dane Dalmatian)

A Great Dane Dalmatian standing seriously under the sun wearing a blue harness
Meet King, a Dalmatian and Great Dane mix standing outdoors – Image source

The Dalmatian and Great Dane mix is one you don’t see too often. They’re friendly, affectionate, active, and will make a great watchdog.

This unique mixed breed will mostly take after the Great Dane parent in its size and coat. However, it will typically have spotted markings on its coat, resembling the Dalmatian parent.

27. French Bulldog Great Dane mix (AKA French Bull Dane)

The French Bull Dane may be stubborn to train, but they’ll be affectionate. They’ll get along well with the family, other people, and other pets.

Of course, this may also cause separation anxiety if they’re away from their family for long periods.

This doggo will be protective of the ones they love, but they won’t get aggressive with others. They have a low to moderate energy level, a perfect mixture of their parent breeds.

They can resemble either parent but might be on the smaller side, taking after the French Bulldog.

28. Newfoundland Great Dane mix (AKA Great Dane Newfoundland)

A cuddly Great Dane Newfoundland lounging outside on the grass
Meet Murphy, a Newfoundland Great Dane mix in the garden – Image source

First, the Newfoundland Great Dane mix will need an experienced owner and early socialization. Due to their large size, they might be hard to maintain, and training could be difficult.

However, the Great Dane Newfoundland will be affectionate and want to spend a lot of time with you. Of course, if they’re away from you for long periods, they may get separation anxiety.

Be warned: this giant dog is a shedder and will have long hair that requires regular grooming and brushing to keep it at bay.

29. Shar Pei Great Dane mix (AKA Great Dane Shar Pei)

An adorable Great Dane Shar Pei wearing a blue bandana
Meet Wally, an adorable Shar Pei Great Dane mix – Image source

This is another mutt that will be great for experienced dog owners. While they’re affectionate and will love spending time with you, they might be stubborn when it comes to training.

They could also be friendly from their Great Dane parent or be on the more aggressive side from their Shar Pei parent. Either way, due to their large size, they’ll make a great watchdog.

30. Chow Chow Great Dane mix (AKA Great Chowdane)

A huggable Great Chowdane puppy sitting on the grass
Meet Moose, a cute Chow Chow Great Dane mix puppy – Image source

This large mixed breed will have a medium-length coat as a mixture between its Chow Chow parent and Great Dane parent.

This pup will need long walks and plenty of exercise to help keep them healthy and maintain their energy levels. They’re a very active, intelligent dog who is eager to please and loyal.

31. Cocker Spaniel Great Dane mix (AKA Great Cocker Spaniel)

A charming Great Cocker Spaniel in a dog bed
Meet Brownie, a brown Cocker Spaniel Great Dane mix comfortably laying down – Image source

This dog mix will need a lot of attention and is very lovable. The Great Cocker Spaniel will be loyal and affectionate toward you and the rest of the family.

This medium-sized pup will have fur that’s short to medium in length with minimal shedding so that grooming will be a breeze. It can look like either the Great Dane or the Cocker Spaniel parent.

32. Rhodesian Ridgeback Great Dane mix (AKA Rhodesian Great Dane)

A Rhodesian Great Dane happily laying under the sun
Meet Diamond, a beaming Rhodesian Ridgeback Great Dane mix – Image source

This mixed breed will love the outdoors as they’re pretty active. They’re brilliant dogs that will need a lot of mental and physical activities.

What’s great about this fido is that they’re quick to learn and easy to train. They require a lot of attention and can get lonely and bored quickly when alone for long periods.

The Rhodesian Ridgeback mixed with the Great Dane will make a rather large dog weigh up to 175 pounds (79 kg).

33. Bernese Mountain Dog Great Dane mix (AKA Berner Dane)

A Berner Dane puppy sitting on the stair
Meet Duchess, a snow-loving Bernese Mountain Dog Great Dane mix – Image source

The Berner Dane is another huge dog. They can take after either pet parent so that the coat will vary. They might have a long coat like the Bernese Mountain Dog or a short, more manageable coat from the Great Dane.

This doggo is friendly and calm, getting along with everyone in the whole family.

34. Dachshund and Great Dane mix (AKA Great Dane Dachshund)

A brindle Great Dane Dachshund wearing a blue collar
A Dachshund and Great Dane mix full-body image standing – Image source

Similar to the Chihuahua mix, these mixed breed dogs are hard to come by. Due to their sizing differences, it’s not recommended to breed these pups together. However, it is possible.

The Great Dane Dachshund will most likely take after the Dachshund’s sizing with an elongated body but have enlarged paws from the Great Dane.

This fido is a quick learner, eager to please, and easy to train in terms of personality. They’re gentle, affectionate and loyal to their owners.

35. Corgi Great Dane mix (Corgi Great Dane)

A Corgi Great Dane tilting its head while sitting down
A Corgi Great Dane mix adorably sitting down – Image source

The Corgi and Great Dane mix are friendly and active. They’re good with kids making them ideal for families and easy-going, making them great for first-time dog owners.

While this pup can look like either the Corgi or the Great Dane, they’ll most likely be medium in size with a short coat.

Which Great Dane mixes are your favorites?

There are many Great Dane mixed breeds! Other less popular mixes are the Bloodhound and Great Dane or a Blue Heeler and Great Dane.

Most of these hybrids will be large, so you’ll need a fenced-in yard and plenty of dog food!

These pups are family-friendly and will be loyal to boot.

Which Great Dane mix will you bring home today? Let us know which one in the comments.

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